Pipeline

Expanded Universal Donor Stem and Progenitor Cell Therapy for Hematological Malignancies.

Pre-Clinical
Phase I
Phase II
Phase III
Stem Cell Transplant
 
 
HEME MALIGNANCIES
 
 
CBT + OTS (TBI-based)
 
 
CBT + OTS Ablative, non - TBI
Non-Transplant
 
 
Heme Malignancies
 
 
CIN adult
 
 
CIN peds
 
 
Sepsis
 
 
Medical Counter Measure
 
 
ARS
 
 
Non-malignant disease
 
 
Gene Therapy
Immunomodulatory
 
 
Stem Cell Transplants
 
 
GvHD prophlaxis
 
 
Solid Organ Transplant
 
 
Induction of Tolerance
Immunotherapy
 
 
Malignant Diseases
 
 
Progenitor Cell CARs
 
 
Malignant Relapse
 
 
NK Cells/DLI

Glossary:

ARS – Acute Radiation Syndrome
CAR – Chimeric Antigen Receptor
CBT – Cord Blood Transplant
CIN – Chemotherapy-Induced Neutropenia
DLI – Donor Lymphocyte Infusion
GvHD – Graft versus Host Disease
NK cells – Natural Killer cells
OTS cord blood product – Off-the-Shelf expanded cord blood
TBI – Total Body Irradiation